More from Jannik Sinner reflecting on his recent form and his second-round defeat:

"I always try to look the positive side. If you watch the whole clay swing, [it has gone] very well. I played really good, winning three tournaments in a row on clay.

"Coming here, also how I was playing tennis, I felt very well, hitting the ball in a good way, moving well and today was just not meant to be.

"I think many things together caused this problem today, but again, it can happen.

"I just need my time now to process what went wrong here and positives also that we can put in good practice weeks before Wimbledon.

"After Wimbledon, we have important tournaments coming up - there are still plenty to play this year."

Jannik Sinner, asked about what happened from when he led 5-1 in the third set onwards:

"I struggled and started to feel very dizzy, very low on energy. I tried to serve it out but didn't have a lot of energy. In the fourth set, I let it go a little bit trying to have a bit more energy in the fifth. The first one was a very important game and I couldn't hold. Then it went a bit downwards.

"I woke up this morning, didn't feel very well and tried to keep the points very short. Also in the beginning I was hitting very clean, very good, and then I just kind of hit the wall, and that's it."

Asked when he started to feel things began feeling difficult in the match:

"The middle of the third set, even though I was playing some great tennis, but I really couldn't find any energy today.

"It was a tough spot to be in. But, again, this is the sport. It was warm but not crazy warm. I feel like it was quite OK to play. Really it was nothing against the heat, nothing against the weather. It was just me today, but it happens."

Amanda Anisimova's opponent Julia Grabher of Austria has retired from their second-round match, which means that the American has got an easy passage through to round three.

The sixth seed will play the winner of the match between French player Diane Parry and 30th seed Ann Li of the USA, which is currently on Court Philippe-Chatrier.

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Jannik Sinner has been speaking to the media following his second-round loss to Juan Manuel Cerundolo - we will bring you some of what the world number one had to say shortly...

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With the shock of Jannik Sinner going out, it's easy to forget that there's plenty of other tennis still going on this afternoon.

Last year's Wimbledon finalist Amanda Anisimova is on Court Suzanne-Lenglen and has taken the first set 6-0 in just 19 minutes against Austria's Julia Grabher.

American Anisimova missed all the clay events before Roland Garros with a wrist injury but looks pretty sharp out there.

The 24-year-old reached the finals of both Wimbledon and US Open last year but it was here at the French Open where she first burst into the spotlight, reaching the semi-finals as a 17-year-old back in 2019.

Regardless of his early exit in Paris, Jannik Sinner will remain world number one after this tournament.

Sinner, who in 2024 became the first Italian to reach number one in the ATP rankings, has held the position for 73 weeks in total.

He and Carlos Alcaraz have been alternating at the top, but with Alcaraz out of action for the grass season, Sinner is set for an extended stay at the top.

At the top of this page, you can have your say on who you think will win the men's title, following Jannik Sinner's surprise exit earlier.

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Jannik Sinner arrived in Paris off the back of a trio of Masters titles in Monte-Carlo, Madrid and Rome, and headed into his second-round tie unbeaten in 18 matches on clay in 2026.

But has he suffered because of his busy schedule?

"He's probably played too much," said 1988 finalist Henri Leconte on TNT Sports. "I thought after Madrid, you stop and not play Rome."

Former British number one Tim Henman agreed: "You play one of Madrid or Rome."

It's the earliest Jannik Sinner has lost at a Grand Slam since he was beaten by world number 74 Daniel Altmaier at the 2023 French Open - and even then, he had two match points in an epic that lasted five hours and 26 minutes.

In the 11 Grand Slams since then (until today), he had only failed to reach the semi-finals twice, winning four of those tournaments.

Tim Henman
Former British number one on TNT Sports

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Everyone was saying Sinner’s going to win. He’s been unbeatable in the past few months. It’s amazing how it’s unravelled in the heat.

Sinner is still very young. He’s going to win Roland Garros one day.

I’m sure him and his team will analyse this. It was against the American – Eliot Spizzirri - in Melbourne when he struggled [in the heat].

Juan Manuel Cerundolo caused a massive shock on Court Philippe-Chatrier by beating the world number one and French Open favourite Jannik Sinner.

His older brother, Francisco Cerundolo, is also into round three with a four-set win against Frenchman Hugo Gaston.

If their respective winning runs continue, they could meet in the semi-finals...

Tim Henman
Former British number one on TNT Sports

[I've said] it's only going to be an injury or an illness [to stop Sinner]. And that is the physical side of it [today].

It's not like he had a bad day at the office because of his tennis - he was two sets and 5-1 [up].

But his five-set record, he struggles. In the heat, he struggles. And that's exactly what's happened.

BBC Radio 5 Sports Extra

The live text updates will continue, but coverage on BBC Radio 5 Sports Extra is going to pause for a little while.

We'll let you know when it resumes.

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Jannik Sinner's defeat also means he will have to wait another year for his chance to complete his set of Grand Slam titles, something rival Carlos Alcaraz did at the Australian Open.

Sinner had already won the Australian and US Opens, and collected the Wimbledon title last year.

But he won't be adding his name to the list of six men - Rod Laver, Andre Agassi, Roger Federer, Rafael Nadal, Novak Djokovic and Alcaraz - who have achieved the full set in the Open era.

No surprises about what the big story of the day is!

But elsewhere...

• 17-year-old Frenchman Moise Kouame has continued his dream run at Roland Garros - he beat Adolfo Daniel Vallejo in five sets to reach the third round.
• Naomi Osaka and Iva Jovic have booked third-round spots in the women's draw.
• Still to come... Aryna Sabalenka, Amanda Anisimova, Coco Gauff and Great Britain's Katie Boulter.

Russell Fuller
BBC tennis correspondent on BBC Radio 5 Sports Extra

It is not easy to be able to play like that against an injured opponent, so a huge credit to Cerundolo for doing just that. This was so impressive, the way he handled it and he never let Sinner back into the match.

I do feel sorry for Sinner, because physically it is more difficult for him to deal with these conditions as a redhead and his complexion makes it difficult.

I don't think we can say that he didn't prepare properly but I would say he has played and won too many matches to get to this point. He was relentless and it was probably a combination of many factors.

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With no Carlos Alcaraz because of injury, and now Jannik Sinner eliminated in the second round, that opens the men's singles draw right up at Roland Garros.

Is this the time for Novak Djokovic to clinch that record-breaking 25th Grand Slam singles title? Will Alexander Zverev finally land his first? Or will someone else emerge from the pack?

We've got a fascinating week and a bit ahead of us in Paris.

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That was Jannik Sinner's first defeat since mid-February, and ends his 30-match winning streak.

It also means that for the first time since the 2023 US Open, someone other than Carlos Alcaraz or Jannik Sinner will win a men's Grand Slam singles title.

Annabel Croft
Former British number one on BBC Radio 5 Sports Extra

I thought Cerundolo gave a very humble speech there and it was like he didn't deserve the win but he absolutely does.

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Juan Manuel Cerundolo, speaking on court after his five-set victory over world number one Jannik Sinner:

"It's tough for him, he was leading the match and I couldn't win more than three games in a set.

"I was a little bit lucky and I feel sorry for him, he was serving to win the match. Then I don't know what happened, I think he was cramping. Of course I feel sorry for him and I hope he recovers."

On reaching the third round at a Grand Slam for the first time in his career: "I'm super happy, I will try to keep playing my best. I like to play this tournament because clay is my best surface and I hope to be ready for the next match."